Another cultivar that enjoys prominence in Simonsvlei’s portfolio is the only true South African grape varietal, Pinotage, which is mostly grown as bush vines. In the cooler parts of the valley, the grapes tend to have more floral flavours, whilst the Pinotage planted in the warmer areas display prominent berry or plum aromas. Other red cultivars include the noble grape varietal Cabernet Sauvignon, and Merlot, the classic blending partner for Cabernet.

The region’s soil and climate are also favourable for the production of quality white grapes. Simonsvlei is well known for its high quality Chenin Blanc, Sauvignon Blanc, and Chardonnay wines. The Sauvignon Blanc vineyards perform better in the cooler parts of the region and are planted mostly in the Klipheuwel and Durbanville area. In the latter region, the grapes benefit greatly from the cooling breezes that blow in from the nearby cold Atlantic Ocean.

Sauvignon Blanc planted in the Klipheuwel and Durbanville areas display a vegetative/herbaceous character, rather than the more common gooseberry flavours. Simonsvlei is one of only five South African cellars still making wine from the underrated Bukettraube grape. This varietal is known for its floral aromas and distinctive Muscat bouquet.